Reformulation
Developing delivery approaches that may improve how an existing drug can be used.
Drug Rescue
Generating new opportunities from known drugs
Applying chemistry, formulation and drug-discovery capabilities to renew the therapeutic potential of established molecules.
The opportunity
Valuable pharmacology can remain underused
Drug candidates and approved medicines may be limited by delivery, adverse effects, formulation or an initial therapeutic positioning that does not capture their full potential.
A drug that fails in the clinic — or delivers only limited benefit — may still hold the key to an unmet medical need.
The platform
Reformulate. Recombine.
Drug Rescue applies 4Ammonium’s chemistry, formulation expertise and proprietary technologies to uncover new opportunities in existing clinical and preclinical data.
Therapeutic combinations
Exploring combinations intended to improve efficacy or mitigate adverse effects.
Development route
Evidence before expansion
Each opportunity is assessed individually according to the molecule’s regulatory status, available evidence and proposed therapeutic application.
Assess
Review the existing pharmacology, limitations and evidence around the compound.
Define
Select the formulation or combination hypothesis to investigate.
Validate
Generate the evidence required to determine whether the opportunity should advance.
Partnering
Bring us a Drug Rescue opportunity
Contact us to discuss a renewed therapeutic opportunity.
Discuss Drug Rescue with us